Saving Minds http://savingminds.libsyn.com/website Pinecast (https://pinecast.com) enProMIS Neurosciences ProMIS Neurosciences harryjkrinsky@gmail.com no Saving Minds http://savingminds.libsyn.com/website https://storage.pinecast.net/podcasts/covers/0d5c0a23-ee18-46a3-a05b-54c61d4ecf9c/Purple_brain.jpg episodic Copyright 2026 The future of medicine for Alzheimer’s and Parkinson’s diseases Episode 31 – Audio white paper: Perspective on Aducanumab’s Nov. 6 Advisory Committee https://pinecast.com/guid/aff0e7e2-efc7-4d3c-aed3-e8f3ab020307 Mon, 02 Nov 2020 17:32:27 -0000 00:21:53 https://saving-minds.pinecast.co/episode/aff0e7e2efc74d3c/episode-31-audio-white-paper-perspective-on-aducanumab-s-nov-6-advisory-committee no 1 Episode 30 – Dr. Scott Napper on an Alzheimer’s Vaccine https://pinecast.com/guid/3fbeccc4-2c1e-4523-97ce-db3bede61323 Tue, 27 Oct 2020 22:11:28 -0000 00:12:00 https://saving-minds.pinecast.co/episode/3fbeccc42c1e4523/episode-30-dr-scott-napper-on-an-alzheimer-s-vaccine no 1 Episode 29 – Detecting, treating, and preventing Alzheimer’s disease: Dr. Neil Cashman explains https://pinecast.com/guid/ca46d35c-6c98-4326-8c80-00757a381a49 Fri, 09 Oct 2020 14:44:36 -0000 00:08:54 https://saving-minds.pinecast.co/episode/ca46d35c6c984326/episode-29-detecting-treating-and-preventing-alzheimer-s-disease-dr-neil-cashman-explains no 1 Episode 28 – Dr. Josè Luis Molinuevo of the BarcelonaBeta Brain Research Center on his biomarker presentation at AAIC https://pinecast.com/guid/53a42a54-08da-48eb-8623-c33f5750bb60 Wed, 09 Sep 2020 11:00:00 -0000 00:12:40 https://saving-minds.pinecast.co/episode/53a42a5408da48eb/episode-28-dr-jos-luis-molinuevo-of-the-barcelonabeta-brain-research-center-on-his-biomarker-presentation-at-aaic no 1 Episode 27 – Using Artificial Intelligence to speed Alzheimer’s studies https://pinecast.com/guid/af417561-c7cf-4838-a169-8b722630859b Thu, 30 Jul 2020 16:47:10 -0000 00:24:42 https://saving-minds.pinecast.co/episode/af417561c7cf4838/episode-27-using-artificial-intelligence-to-speed-alzheimer-s-studies no 1 Episode 26 – A diagnostic test for Alzheimer’s disease https://pinecast.com/guid/17be71b6-f521-4f3b-8f3f-ee04e4dbcd3c Thu, 09 Jul 2020 09:30:00 -0000 00:17:18 https://saving-minds.pinecast.co/episode/17be71b6f5214f3b/episode-26-a-diagnostic-test-for-alzheimer-s-disease Episode Notes

Shanti and Elliot talk to Dr. James Kupiec about a diagnostics test for Alzheimer's disease.

]]> no 1 Episode 25 – Trusting Covid-19 antibody testing—the CDC weighs in https://pinecast.com/guid/1731758e-7323-4913-9035-ca65f2f23db6 Wed, 17 Jun 2020 20:35:41 -0000 00:18:15 https://saving-minds.pinecast.co/episode/1731758e73234913/episode-25-trusting-covid-19-antibody-testing-the-cdc-weighs-in Episode Notes

Shanti and Elliot discuss recent developments in antibody testing for Covid-19

]]> no 1 Episode 24 – New Ways to Attack ALS and Other Protein Misfolding Diseases with Johanne Kaplan 87a5b28a-a9eb-409e-9c81-1974d1b008f8 Thu, 21 May 2020 10:00:00 -0000 00:10:45 https://saving-minds.pinecast.co/episode/bebc166c68ee438b/episode-24-new-ways-to-attack-als-and-other-protein-misfolding-diseases-with-johanne-kaplan Elliot and Shanti talk to Johanne Kaplan about a new way to attack ALS and other protein misfolding diseases,

]]> no 1 Episode 23 – Introducing Intrabodies with Dr. Johanne Kaplan. 430535d9-dbdb-4e84-96b6-1e808cbb08ba Thu, 30 Apr 2020 09:30:00 -0000 00:12:00 This week Shanti and Elliot discuss Intrabodies with Dr. Johanne Kaplan https://saving-minds.pinecast.co/episode/fcd04d5c9c854978/episode-23-introducing-intrabodies-with-dr-johanne-kaplan- This week Shanti and Elliot discuss Intrabodies with Dr. Johanne Kaplan

]]> no 1 Episode 22 – Worried about aducanumab? Don’t be. Dr. Jim Kupiec explains dc01b401-035e-40c0-bce5-0071b252ed43 Fri, 24 Apr 2020 21:52:14 -0000 00:12:41 Dr. Jim Kupiec explains why there is nothing to worry about regarding the recent news about aducanumab. https://saving-minds.pinecast.co/episode/bb0bf08964964c30/episode-22-worried-about-aducanumab-don-t-be-dr-jim-kupiec-explains Dr. Jim Kupiec explains why there is nothing to worry about regarding the recent news about aducanumab.

]]> no 1 Episode 21 – “For a COVID-19 antibody test, selectivity is key.” f8341e00-91d1-46fc-8fbc-1cd0b3bd6387 Wed, 15 Apr 2020 11:00:00 -0000 00:18:46 Shanti and Elliot announce that ProMIS is beginning to develop a test for Covid-19. They discuss how ProMIS can leverage its existing expertise. https://saving-minds.pinecast.co/episode/9234dcdb778a4e45/episode-21-for-a-covid-19-antibody-test-selectivity-is-key- Shanti and Elliot announce that ProMIS is beginning to develop a test for Covid-19. They discuss how ProMIS can leverage its existing expertise.

]]> no 1 *Re-Release* Episode 4 – How do Biomarkers Work? 406acd14-55ad-4365-9f00-19076e24bb5d Sat, 28 Mar 2020 20:10:34 -0000 00:13:19 We are re-releasing a popular episode about Biomarkers and how they work! https://saving-minds.pinecast.co/episode/1f935986e3d34975/re-release-episode-4-how-do-biomarkers-work- We are re-releasing a popular episode about Biomarkers and how they work!

]]> no Episode 20 –Dr. José Luis Molinuevo of the BarcelonaBeta Brain Research Center on the Future of Alzheimer's Disease 422526ad-1d31-43bf-9b24-c2661a9bf702 Tue, 10 Mar 2020 19:11:53 -0000 00:27:48 Shanti and Elliot talk to Dr. José Luis Molinuevo of the BarcelonaBeta Brain Research Center on the Future of Alzheimer's Disease https://saving-minds.pinecast.co/episode/d899c05d270d4c93/episode-20-dr-jos-luis-molinuevo-of-the-barcelonabeta-brain-research-center-on-the-future-of-alzheimer-s-disease Shanti and Elliot talk to Dr. José Luis Molinuevo of the BarcelonaBeta Brain Research Center on the Future of Alzheimer's Disease

]]> no Episode 19 – Dr. Stephen Salloway, Rhode Island’s Man of the Year, on a brighter future for Alzheimer’s disease 78571266-3f22-4f86-9dcf-77c4a24bc726 Mon, 17 Feb 2020 19:51:08 -0000 00:23:04 Dr. Stephen Salloway and Dr. James Kupiec reflect on Aducanumab, the exciting progress that has been made in the AD research community over the last 20 years, and the future of AD research. https://saving-minds.pinecast.co/episode/0c75501233be47c4/episode-19-dr-stephen-salloway-rhode-island-s-man-of-the-year-on-a-brighter-future-for-alzheimer-s-disease Dr. Stephen Salloway and Dr. James Kupiec reflect on Aducanumab, the exciting progress that has been made in the AD research community over the last 20 years, and the future of AD research.

]]> no Episode 18 – Dr. Sharon Cohen Deconstructs the Aducanumab Data From CTAD 8fc5ad27-2c54-4071-bae0-1ae9a481be33 Wed, 11 Dec 2019 18:48:17 -0000 00:32:06 This week Shanti and Elliot talk to Dr. Sharon Cohen, director of Toronto Memory Program. They discuss the recent news surrounding aducanumab, as well as Dr. Cohen's recent trip to CTAD. https://saving-minds.pinecast.co/episode/4dd3a251190a4908/episode-18-dr-sharon-cohen-deconstructs-the-aducanumab-data-from-ctad This week Shanti and Elliot talk to Dr. Sharon Cohen, director of Toronto Memory Program. They discuss the recent news surrounding aducanumab, as well as Dr. Cohen's recent trip to CTAD.

]]> no Episode 17 – The Data Behind Biogen's Recent Decision with Dr. James Kupiec a88325e7-2df8-4a0e-86d7-bb65f6de1a4f Tue, 19 Nov 2019 04:10:37 -0000 00:18:26 This week Shanti and Elliot discuss the data behind Biogen's recent decision to revive their Aducanumab study. https://saving-minds.pinecast.co/episode/71d0e06a514743b7/episode-17-the-data-behind-biogen-s-recent-decision-with-dr-james-kupiec This week Shanti and Elliot discuss the data behind Biogen's recent decision to revive their Aducanumab study.

]]> no Episode 16 – In the news: Biogen and Neuroinflammation with Dr. Johanne Kaplan 52baf491a66149a5a79d40ee19dc1329 Wed, 06 Nov 2019 18:09:46 -0000 00:13:41 This week Shanti and Johanne discuss the recent news coming out of Biogen and how Neuroinflammation relates to Alzheimer's. https://saving-minds.pinecast.co/episode/4266e036b90744ab/episode-16-in-the-news-biogen-and-neuroinflammation-with-dr-johanne-kaplan This week Shanti and Johanne discuss the recent news coming out of Biogen and how Neuroinflammation relates to Alzheimer's.

]]> no Episode 15 – Protein Misfolding Diseases with Dr. Lary Walker 3453bd6c68a94890a1c4629685613b10 Fri, 04 Oct 2019 14:08:49 -0000 00:17:49 This week Shanti and Elliot talk to Dr. Lary Walker, a research professor at Emory University. They discuss what Alzheimer’s, Parkinson’s and more have in common. https://saving-minds.pinecast.co/episode/25cd6a10bc23416f/episode-15-protein-misfolding-diseases-with-dr-lary-walker This week Shanti and Elliot talk to Dr. Lary Walker, a research professor at Emory University. They discuss what Alzheimer’s, Parkinson’s and more have in common.

]]> no Episode 14 – Finding Treatment for Alzheimer's and Other Diseases with Brain Canada's Inez Jabalpurwala c74dc8c9f2684b1fa7b67bdb5e04ec99 Wed, 11 Sep 2019 17:49:23 -0000 00:20:01 This week Shanti and Elliot are joined by Brain Canada's CEO Inez Jabalpurwala. They discuss the wonderful work that Brain Canada has been doing, and the next steps in the search for a cure for Alzheimer's, Parkinson's and other diseases. https://saving-minds.pinecast.co/episode/bdfd2ed149c144a0/episode-14-finding-treatment-for-alzheimer-s-and-other-diseases-with-brain-canada-s-inez-jabalpurwala This week Shanti and Elliot are joined by Brain Canada's CEO Inez Jabalpurwala. They discuss the wonderful work that Brain Canada has been doing, and the next steps in the search for a cure for Alzheimer's, Parkinson's and other diseases.

]]> no Episode 13 – Understanding Multiple System Atrophy, Prions and Neuron Death f5a5a5e1c43046df9c9f3fdc824a799a Fri, 30 Aug 2019 19:03:43 -0000 00:15:58 This week Shanti and Elliot discuss Multiple System Atrophy, prions and how greater understanding of each can help other neurodegenerative diseases. https://saving-minds.pinecast.co/episode/a80523d56922457e/episode-13-understanding-multiple-system-atrophy-prions-and-neuron-death This week Shanti and Elliot discuss Multiple System Atrophy, prions and how greater understanding of each can help other neurodegenerative diseases.

]]> no Episode 12 – A Deeper Dive Into Biomarkers with Dr. James Kupiec Reporting on AAIC Research bf7c97623efa427c994a4800e68f868a Thu, 22 Aug 2019 00:16:16 -0000 00:16:35 This week Shanti is joined by Dr. James Kupiec, Chief Medical Officer at ProMIS Neurosciences. Shanti and Dr. Kupiec do a deep dive on Biomarkers and discuss recent research coming out of AAIC. https://saving-minds.pinecast.co/episode/de13ef56f5bf4281/episode-12-a-deeper-dive-into-biomarkers-with-dr-james-kupiec-reporting-on-aaic-research This week Shanti is joined by Dr. James Kupiec, Chief Medical Officer at ProMIS Neurosciences. Shanti and Dr. Kupiec do a deep dive on Biomarkers and discuss recent research coming out of AAIC.

]]> no Episode 11 – What Is TDP43 and What Are We Going to Do About It? 1c4bc195f9fe47849b8478369b978749 Mon, 12 Aug 2019 04:53:38 -0000 00:14:03 Elliot is back to discuss the TDP43 protein, which has been implicated in the development of a recently discovered form of dementia as well as ALS. Shanti and Elliot talk about why TDP43 is important, and the efforts to neutralize the misfolded... https://saving-minds.pinecast.co/episode/10037f26950f4654/episode-11-what-is-tdp43-and-what-are-we-going-to-do-about-it- Elliot is back to discuss the TDP43 protein, which has been implicated in the development of a recently discovered form of dementia as well as ALS. Shanti and Elliot talk about why TDP43 is important, and the efforts to neutralize the misfolded protein in the brain before it can destroy brain cells.

]]> no Episode 10 – AAIC 2019 Recap with Dr. Johanne Kaplan ee95a91c7b574e47b2fd8d264385b570 Tue, 23 Jul 2019 20:48:02 -0000 00:13:23 This week Shanti and Dr. Johanne Kaplan recap AAIC 2019 and discuss the exciting data that came out of the conference. For more information check out https://saving-minds.pinecast.co/episode/d1c32093d5d24622/episode-10-aaic-2019-recap-with-dr-johanne-kaplan This week Shanti and Dr. Johanne Kaplan recap AAIC 2019 and discuss the exciting data that came out of the conference. For more information check out https://promisneurosciences.com/

]]> no Episode 9 – AAIC 2019 Preview with Dr. Johanne Kaplan 640f64d50dbc4fc386246f275afffd3c Fri, 12 Jul 2019 18:19:09 -0000 00:08:42 This week Shanti and Johanne preview AAIC and discuss what the hot topics at the conference are expected to be. https://saving-minds.pinecast.co/episode/c51ae9f5a2b14874/episode-9-aaic-2019-preview-with-dr-johanne-kaplan This week Shanti and Johanne preview AAIC and discuss what the hot topics at the conference are expected to be.

]]> no Episode 8 – 2019 Keystone Symposia Breakdown with Dr. Johanne Kaplan 7252385a65884bdf88016db4591fe5ee Tue, 25 Jun 2019 18:51:10 -0000 00:19:20 This week Shanti discusses some of the most exciting news coming out of the recent 2019 Keystone Symposia with Dr. Johanne Kaplan. https://saving-minds.pinecast.co/episode/7018de573ea14f8f/episode-8-2019-keystone-symposia-breakdown-with-dr-johanne-kaplan This week Shanti discusses some of the most exciting news coming out of the recent 2019 Keystone Symposia with Dr. Johanne Kaplan.

]]> no Episode 7 – Dr. Johanne Kaplan on the Importance of Selectivity 86e8a21e788f4f51a794bd782ba2c03e Wed, 19 Jun 2019 11:00:00 -0000 00:24:00 Shanti is joined by Dr. Johanne Kaplan, the Chief Development Officer at ProMIS Neurosciences. The two discuss Dr. Kaplan's career, and the current challenges researchers must tackle as they continue their search for a way to stop Alzheimer's disease.... https://saving-minds.pinecast.co/episode/ead8423af5eb4eb6/episode-7-dr-johanne-kaplan-on-the-importance-of-selectivity Shanti is joined by Dr. Johanne Kaplan, the Chief Development Officer at ProMIS Neurosciences. The two discuss Dr. Kaplan's career, and the current challenges researchers must tackle as they continue their search for a way to stop Alzheimer's disease. The two also discuss Dr. Kaplan's recent paper on the importance of selectivity in drug development for Alzheimer's.

]]> no Episode 6 – The "One-Two Punch" of Abeta and Tau 82c623cdb95141ef9c81fb1ebe275b5d Tue, 28 May 2019 10:45:00 -0000 00:13:54 Toxic tau and amyloid-beta are the two most validated drug targets for an Alzheimers disease therapy. Elliot and Shanti discuss tau, its role as a root cause of Alzheimer's disease and its involvement in 80 other diseases known as tauopathies. https://saving-minds.pinecast.co/episode/892c6574486a4153/episode-6-the-one-two-punch-of-abeta-and-tau Toxic tau and amyloid-beta are the two most validated drug targets for an Alzheimers disease therapy. Elliot and Shanti discuss tau, its role as a root cause of Alzheimer's disease and its involvement in 80 other diseases known as tauopathies.

]]> no Episode 5 – Major Late-stage Alzheimer's Failures a4490a2b21074b91a818fba07c020b0c Sat, 25 May 2019 16:16:30 -0000 00:15:09 Dr. Goldstein and Shanti breakdown the news of the week. This week they discuss two major late-stage failures for promising Alzheimer's drugs, a new syndrome that is similar to Alzheimer's, and some important biomarker developments. https://saving-minds.pinecast.co/episode/1f21681bfea14e8d/episode-5-major-late-stage-alzheimer-s-failures Dr. Goldstein and Shanti breakdown the news of the week. This week they discuss two major late-stage failures for promising Alzheimer's drugs, a new syndrome that is similar to Alzheimer's, and some important biomarker developments.

]]> no Episode 4 – How do Biomarkers Work? 42b67f9c27d747cdac155b3beba674ad Wed, 27 Mar 2019 23:15:07 -0000 00:13:19 This is part two of our exploration of biomarkers. Elliot and Shanti discuss how biomarkers work and how they will play a critical role in the future of drug development for the various brain-wasting diseases. https://saving-minds.pinecast.co/episode/01163c3a32c746a4/episode-4-how-do-biomarkers-work- This is part two of our exploration of biomarkers. Elliot and Shanti discuss how biomarkers work and how they will play a critical role in the future of drug development for the various brain-wasting diseases.

]]> no 1 Episode 3 – Why Biomarkers Matter a8f157bfa2844f85bd355b209dac62a1 Fri, 15 Mar 2019 22:22:04 -0000 00:13:17 Dr. Goldstein and Shanti discuss why biomarkers are becoming increasingly important in the medical community. They also discuss how biomarkers are uniquely important in the quest for a cure for Alzheimer's. https://saving-minds.pinecast.co/episode/b4dfe57fbd914441/episode-3-why-biomarkers-matter Dr. Goldstein and Shanti discuss why biomarkers are becoming increasingly important in the medical community. They also discuss how biomarkers are uniquely important in the quest for a cure for Alzheimer's.

]]> no 1 Episode 2 – Understanding Parkinson's Disease 59b0e2ec74934d359d3e25afc1f29201 Mon, 11 Mar 2019 06:35:46 -0000 00:15:12 This week Dr. Goldstein and Shanti discuss Parkinson's disease. They discuss the underlying cause of Parkinson's, treatment options, side effects and the connection between Parkinson's and Alzheimer's https://saving-minds.pinecast.co/episode/f2b0b50f4cfe49ce/episode-2-understanding-parkinson-s-disease This week Dr. Goldstein and Shanti discuss Parkinson's disease. They discuss the underlying cause of Parkinson's, treatment options, side effects and the connection between Parkinson's and Alzheimer's

]]> no 1 Episode 1 – The Alzheimer's Public Health Crisis 40a20e9939d84dc589f993988e69537f Sun, 24 Feb 2019 02:19:46 -0000 00:14:11 This week our hosts Dr. Elliot Goldstein MD and Shanti Skiffington provide a summary of the current efforts to find a cure for Alzheimer's disease. https://saving-minds.pinecast.co/episode/eea9fa2a27194883/episode-1-the-alzheimer-s-public-health-crisis This week our hosts Dr. Elliot Goldstein MD and Shanti Skiffington provide a summary of the current efforts to find a cure for Alzheimer's disease.

]]> no 1